Electrocatalytic properties of prussian blue nanoparticles supported on poly(m-aminobenzenesulfonic acid)–functionalized single-walled carbon nanotubes toward the detection of dopamine
- Adekunle, Abolanle S., Farah, Abdullahi M., Pillay, Jeseelan, Ozoemena, Kenneth I., Mamba, Bhekie B., Agboola, Bolade O.
- Authors: Adekunle, Abolanle S. , Farah, Abdullahi M. , Pillay, Jeseelan , Ozoemena, Kenneth I. , Mamba, Bhekie B. , Agboola, Bolade O.
- Date: 2013-10-21
- Subjects: Prussian blue nanoparticles , Dopamine , Nanotubes
- Type: Article
- Identifier: uj:5992 , http://hdl.handle.net/10210/8625
- Description: Edged plane pyrolytic graphite electrode (EPPGE) was modified with and without Prussian blue (PB) nanoparticles and polyaminobenzene sulphonated single-walled carbon nanotubes (SWCNTPABS) using the chemical deposition method. The electrodes were characterised using microscopy, spectroscopy and electrochemical techniques. Results showed that edged plane pyrolytic graphite-single-walled carbon nanotubes-prussian blue (EPPGE-SWCNT-PB) electrode gave the best dopamine (DA) current response which increases with increasing PB layers.
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- Authors: Adekunle, Abolanle S. , Farah, Abdullahi M. , Pillay, Jeseelan , Ozoemena, Kenneth I. , Mamba, Bhekie B. , Agboola, Bolade O.
- Date: 2013-10-21
- Subjects: Prussian blue nanoparticles , Dopamine , Nanotubes
- Type: Article
- Identifier: uj:5992 , http://hdl.handle.net/10210/8625
- Description: Edged plane pyrolytic graphite electrode (EPPGE) was modified with and without Prussian blue (PB) nanoparticles and polyaminobenzene sulphonated single-walled carbon nanotubes (SWCNTPABS) using the chemical deposition method. The electrodes were characterised using microscopy, spectroscopy and electrochemical techniques. Results showed that edged plane pyrolytic graphite-single-walled carbon nanotubes-prussian blue (EPPGE-SWCNT-PB) electrode gave the best dopamine (DA) current response which increases with increasing PB layers.
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The in-situ fabrication of high-performance metal-polymernanocomposites, within electro-catalysts, for the detection of dopamine and iodine respectively
- Authors: Brink, Raugmé
- Date: 2018
- Subjects: Nanocomposites (Materials) , Catalysts , Dopamine
- Language: English
- Type: Masters (Thesis)
- Identifier: http://hdl.handle.net/10210/292769 , uj:31821
- Description: M.Sc. (Chemistry) , Abstract: Dopamine (DA) as a well-known neurotransmitters (NT), is a chemical messenger involved in the renal, hormonal, cardiovascular and central nervous system and enables neuronal communication. Dopamine forms part of some crucial metabolic and physiological processes within the body. Various diseases and disorders such as Parkinson’s Disease and Schizophrenia may stem from its imbalance [1, 2]. Certain analytes such as iodide, as an essential micronutrient, may also be indicative of the physiological health of a person. Its imbalance within the physiological system may either cause Goiter or act as a Goitrogen. It has been seen to affect 656 million people worldwide [1, 3]. The development of rapid and sensitive methods for the detection of these electroactive biomolecules and analytes, are important for both clinical and numerous non-clinical applications. The aim of the study was to synthesize metal enriched polymers as electro-catalysts for the efficient and sensitive detection of electroactive analytes. Electro-analytical chemistry has served as an alternative branch for the study of some physiological systems. These electrochemical sensors are attractive due to their high sensitivity, good controllability, rapid response rate and real-time detection [1]. Functional composite materials with unique physical and chemical properties have provided significant benefits for biological detection. Metallic nanoparticles contribute interesting qualities to materials, with respect to their unique electronic and electrocatalytic properties. It is dependent on their size and morphology. The detective potential, sensitivity and selectivity of Ag (0)-2ADPA and Cu(I)-PANI towards dopamine and iodide in an electrochemical based system was investigated during this study.
- Full Text:
- Authors: Brink, Raugmé
- Date: 2018
- Subjects: Nanocomposites (Materials) , Catalysts , Dopamine
- Language: English
- Type: Masters (Thesis)
- Identifier: http://hdl.handle.net/10210/292769 , uj:31821
- Description: M.Sc. (Chemistry) , Abstract: Dopamine (DA) as a well-known neurotransmitters (NT), is a chemical messenger involved in the renal, hormonal, cardiovascular and central nervous system and enables neuronal communication. Dopamine forms part of some crucial metabolic and physiological processes within the body. Various diseases and disorders such as Parkinson’s Disease and Schizophrenia may stem from its imbalance [1, 2]. Certain analytes such as iodide, as an essential micronutrient, may also be indicative of the physiological health of a person. Its imbalance within the physiological system may either cause Goiter or act as a Goitrogen. It has been seen to affect 656 million people worldwide [1, 3]. The development of rapid and sensitive methods for the detection of these electroactive biomolecules and analytes, are important for both clinical and numerous non-clinical applications. The aim of the study was to synthesize metal enriched polymers as electro-catalysts for the efficient and sensitive detection of electroactive analytes. Electro-analytical chemistry has served as an alternative branch for the study of some physiological systems. These electrochemical sensors are attractive due to their high sensitivity, good controllability, rapid response rate and real-time detection [1]. Functional composite materials with unique physical and chemical properties have provided significant benefits for biological detection. Metallic nanoparticles contribute interesting qualities to materials, with respect to their unique electronic and electrocatalytic properties. It is dependent on their size and morphology. The detective potential, sensitivity and selectivity of Ag (0)-2ADPA and Cu(I)-PANI towards dopamine and iodide in an electrochemical based system was investigated during this study.
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Stimulants and growth in children with attention-deficit/hyperactivity disorder
- Negrao, Bianca Lee, Viljoen, Margaretha
- Authors: Negrao, Bianca Lee , Viljoen, Margaretha
- Date: 2011
- Subjects: Attention-deficit-disordered children , Attention-deficit hyperactivity disorder , Adrenergic stimulants , Dopamine , Noradrenaline , Growth attenuation
- Type: Article
- Identifier: http://ujcontent.uj.ac.za8080/10210/390822 , uj:5810 , ISSN 0306-9877 , http://hdl.handle.net/10210/7818
- Description: Initial suggestions that suppression of growth may be an intrinsic characteristic of attention-deficit/hyperactivitydisorder (ADHD) have now largely been disproven. Although controversy persists regarding the possible negative effect of adrenergic stimulants on growth in children with ADHD, the consensus that appears to be reached in the scientific literature is that stimulant usage may cause a manageable attenuation of growth in these children. Since it is known that stimulants increase the amount of dopamine and noradrenaline in the synapse, this writing suggests that these increases in dopamine and noradrenaline are responsible for the growth attenuation in these children. It appears that increased amounts of dopamine and noradrenaline have the ability to inhibit the secretion of growth hormone and growth-related hormones such as prolactin, thyroid hormones, sex hormones and insulin. Therefore, it would be reasonable to suggest that the increases in dopamine and noradrenaline caused by stimulant usage can disrupt the homeostasis of both growth hormone and growth-related hormones, generating the potential for the suppression of growth.
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- Authors: Negrao, Bianca Lee , Viljoen, Margaretha
- Date: 2011
- Subjects: Attention-deficit-disordered children , Attention-deficit hyperactivity disorder , Adrenergic stimulants , Dopamine , Noradrenaline , Growth attenuation
- Type: Article
- Identifier: http://ujcontent.uj.ac.za8080/10210/390822 , uj:5810 , ISSN 0306-9877 , http://hdl.handle.net/10210/7818
- Description: Initial suggestions that suppression of growth may be an intrinsic characteristic of attention-deficit/hyperactivitydisorder (ADHD) have now largely been disproven. Although controversy persists regarding the possible negative effect of adrenergic stimulants on growth in children with ADHD, the consensus that appears to be reached in the scientific literature is that stimulant usage may cause a manageable attenuation of growth in these children. Since it is known that stimulants increase the amount of dopamine and noradrenaline in the synapse, this writing suggests that these increases in dopamine and noradrenaline are responsible for the growth attenuation in these children. It appears that increased amounts of dopamine and noradrenaline have the ability to inhibit the secretion of growth hormone and growth-related hormones such as prolactin, thyroid hormones, sex hormones and insulin. Therefore, it would be reasonable to suggest that the increases in dopamine and noradrenaline caused by stimulant usage can disrupt the homeostasis of both growth hormone and growth-related hormones, generating the potential for the suppression of growth.
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