Abstract
William Whewell's 19th-century views are seldom given a prominent place in the history of the philosophy of science. There is, however, a key feature of his account that is, upon historical analysis, prescient of later developments, notably in pragmatism. Whewell calls this the "fundamental antithesis of philosophy", which centres around the idea that there is no clear demarcation between subject and object (between mind and world or theory and fact). In this article, I trace this notion's genealogy. It originated with Kant, who influenced Whewell. Whewell then developed it into a detailed thesis, one that influenced Peirce. It is identifiable in Quine, then (middle) Putnam, and now Cheryl Misak and Steven Levine (aka the new pragmatists). The purpose is to identify a previously overlooked lineage of influence running through the history of philosophy. Whewell's antithesis might also offer a way to resist both the relativism that tends to accompany post-modern styles of pragmatism and the pretensions to a God's-eye view latent in analytic metaphysics.