Abstract
Abstract:
There is rapidly growing interest in the synthesis and use of substituted 1,2,3-
triazoles. We report an easy and interesting procedure that demonstrates the
effectiveness of surface-modified c-Al2O3, which is reusable, efficient, catalytic, safe, and
environmentally acceptable for the regioselective synthesis of 1,5-disubstituted-1,2,3-
triazoles via [3þ2] cycloaddition of phenyl and benzyl azides with a series of aryl
nitroolefins in good yields. No adverse effect on substituents such as nitro, cyano,
hydroxy, ether linkage, and halogens was observed. The catalyst could easily be recycled
and was reused for nine runs without losing its activity.