Abstract
Solanum retro‡exum (nightshade) is an edible plant that is consumed in some regions of South Africa. Its leaves are a good source
of vitamins, proteins, and minerals. It appears that there is no scientiˆc report about the phytochemical composition of S.
retro‡exum. Here, ultra-performance liquid chromatography coupled to quadruple-time-of-Œight mass spectrometry (UPLCqTOF-
MS) technique was use to achieve an untargeted metabolite ˆngerprinting of this plant. A total of 30 phytochemicals,
including alkaloids, Œavonoids, and cinnamic acids derivatives, were identiˆed from the methanolic leaf extracts. e concentration
of solvent did not a˜ect the type of compounds extracted. e extraction resulted in qualitative yields of molecules such
as quercetin-3-rutinoside, kaempferol-3-0-rutinoside, kaempferol-3-0-glucoside, 3-ca˜eoylquinic acid, 5-ca˜eoylquinic acid, and
3, 4-di-ca˜eoylquinic acid. e present study conˆrms the presence of phytochemical compounds in S. retro‡exum similar to
other Solanum plants.