Abstract
Cancer is a non-communicable disease that occurs following a mutation in the
genes which control cell growth. Breast cancer is the most diagnosed cancer among South
African women and a major cause of cancer-related deaths worldwide. Photodynamic
therapy (PDT) is an alternative cancer therapy that uses photochemotherapeutic agents,
known as photosensitizers. Drug-delivery nanoparticles are commonly used in nanomedicine
to enhance drug-therapeutic efficiency. This study evaluated the photodynamic
effects following treatment with 0.3 mM multiple particles delivery complex (MPDC) and
irradiated with a laser fluence of 10 J/cm2 using a 680 nm diode laser in a breast cancer cell
line (MCF-7)...