Abstract
Different conventional therapeutic procedures are utilized globally to manage cancer cases,
yet the mortality rate in patients with cancer remains considerably high. Developments in the field
of nanotechnology have included novel therapeutic strategies to deal with cancer. Biogenic (green)
metallic silver nanoparticles (AgNPs) obtained using plant-mediated protocols are attractive to
researchers exploring cancer treatment. Biogenic AgNPs present advantages, since they are costeffective,
easy to obtain, energy efficient, and less toxic compared to chemically and physically
obtained AgNPs. Also, they present excellent anticancer abilities thanks to their unique sizes, shapes,
and optical properties. This review provides recent advancements in exploring biogenic AgNPs as
a drug or agent for cancer treatment. Thus, great attention was paid to the anticancer efficacy of
biogenic AgNPs, their anticancer mechanisms, their efficacy in cancer photodynamic therapy (PDT),
their efficacy in targeted cancer therapy, and their toxicity.