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Expression of vitamin D receptor (VDR) and VDR target genes in an African and Caucasian population: the impact of vitamin D and mycobacterial elicitation.
Thesis   Open access

Expression of vitamin D receptor (VDR) and VDR target genes in an African and Caucasian population: the impact of vitamin D and mycobacterial elicitation.

Furaha Florence Asani
Master of Science (MSc), University of Johannesburg
14/01/2014
Handle:
https://hdl.handle.net/10210/8793

Abstract

Mycobacterium tuberculosis Vitamin D receptors Epigenetics Genetic toxicology Cytology
M.Sc. (Biochemistry) Tuberculosis (TB) is an infectious disease that worldwide, is more prevalent in Africans compared to Caucasians. TB also affects males to a greater extent than females. Genetic associations between VDR sequence variants and TB is often inconsistent across different populations. Epigenetic and environmental factors, as well as ethnicity may confound associations found between VDR and TB...
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