Abstract
M.Sc. (Chemistry)
A new method has been developed for the conversion of carbohydrate vicinal diols into the corresponding glycal derivatives. Treatment of suitably protected furanose 1,2-diols with mesyl chloride and triethylamine in anhydrous 1,2-dirnethoxyethane resulted in the formation of 2-0-mesyl-furanosyl chlorides. Reductive elimination of the latter with excess active zinc dust in the presence of iodide furnished furanoid glycals ...