Abstract
D.Sc. (Chemistry)
The aim of this study was directed towards the stereo- and regiospecific introduction of
carbon nucleophiles onto the 1- and 4-positions of glycopyranosides, since these chiral
molecules contain the tetrahidropyran skeleton of a wide range of biologically active
compounds (example the carpenter bee pheromone or the civit cat pheromone) or substructures of more complex natural products, such as the ionophore antibiotics
indanomycin and zincophorin. Two appraoches for the introduction of carbon
substituents onto the 1- and/or 4-positions of unsaturated glycopyranosides were
investigated ...